An innovative web application for managing academic documents

Archiving versions of academic documents in consideration of green thinking was the motivation to develop an innovative tool that could organize academic documents in a centralized database. This paper presents a new web application, which aims to move towards a paperless University model for managing academic documents that are used within an educational institution, such as proposal courses, syllabuses etc. AcaDocMan, the developed application can be used by academic staff and quality assurance officers of institutions who are able not only to manage their course syllabuses but also to generate different consistent document formats for various purposes

Modelling of Multi-Agent Systems: Experiences with Membrane Computing and Future Challenges

Formal modelling of Multi-Agent Systems (MAS) is a challenging task due to high complexity, interaction, parallelism and continuous change of roles and organisation between agents. In this paper we record our research experience on formal modelling of MAS. We review our research throughout the last decade, by describing the problems we have encountered and the decisions we have made towards resolving them and providing solutions. Much of this work involved membrane computing and classes of P Systems, such as Tissue and Population P Systems, targeted to the modelling of MAS whose dynamic structure is a prominent characteristic. More particularly, social insects (such as colonies of ants, bees, etc.), biology inspired swarms and systems with emergent behaviour are indicative examples for which we developed formal MAS models. Here, we aim to review our work and disseminate our findings to fellow researchers who might face similar challenges and, furthermore, to discuss important issues for advancing research on the application of membrane computing in MAS modelling.Comment: In Proceedings AMCA-POP 2010, arXiv:1008.314

FONCTIONS DU TOXIQUE ET FACTEURS SPÉCIFIQUES DE CHANGEMENT PSYCHOTHÉRAPEUTIQUE CHEZ LES ADOLESCENTS ET JEUNES ADULTES USAGERS DES DROGUES

La thèse ici présentée s'inscrit dans la recherche pour comprendre et approfondir les origines, le développement et la dynamique de la psychopathologie de la toxicomanie. L'hypothèse de recherche est que le choix de l'usage des drogues dans le but d'un plaisir immédiat, constitue le facteur central dans la dynamique psychique des patients toxicomanes, aussi différents qu'ils soient du point de vue de l'organisation de leur personnalité. Un tel choix est supposé être à la source de leur stratégie toxique, ce qui leur permet de gérer les tensions psychiques, sous forme d'autoguérison. Nous avons désigné sous le nom de stratégies toxiques les signes qu'une dynamique inconsciente est à l'œuvre et qu'elle peut se modifier. Les contenus, se référant explicitement ou au niveau latent à l'élément toxique, sont des signes que le thérapeute est censé «entendre» et élaborer au plus près. L'objectif est donc de dégager la stratégie toxique à l'œuvre dans le traitement des patients toxicomanes, de repérer ses formes variées d'expression, dans le but de mieux comprendre comment le recours à un moyen réel, tout puissant, inanimé et hors psychisme, tel que la drogue, tend à obscurcir la trace du psychisme et à maintenir le système défensif qui abolit entre autre toute relation thérapeutique, lorsque celle-ci est amenée à s'établir. Ce qui est alors spécifique dans cette clinique n'est pas l'objet-drogue (le toxique), ses effets et ses propriétés, mais les modalités de son choix et de ses fonctions. La rechute ou l'interruption du traitement sont retenus comme critères opérationnels externes, censés révéler l'échec du travail thérapeutique, insuffisamment en prise sur les stratégies toxiques des patients. Pour mieux comprendre la fonction des stratégies toxiques dans le processus, nous avons suivi trois axes de recherche: 1. le repérage et la classification de ces stratégies toxiques; 2. l'analyse des thérapies avec rechute(s), en fonction de la présence et l'évolution ou non de stratégies toxiques; 3. l'analyse des thérapies avancées, sans rechute, en fonction de la prise en considération (et la conscience) du fonctionnement toxique, menant à la diminution ou à l'abandon de ces stratégies. La méthode de l'analyse de contenu adoptée consiste à analyser librement les productions des patients, recueillies dans la situation thérapeutique, qui se définit par le jeu de chaque interlocuteur, fixé par un tiers institutionnel. Les raisons des échecs thérapeutiques sont à rechercher aussi du côté des vécus particuliers des thérapeutes envers leurs patients, aux moments précis de l'introduction des stratégies toxiques dans la relation. De la prise en considération ou non de ces stratégies toxiques à l'œuvre à l'intérieur même du traitement, dépend la possibilité pour ie thérapeute d'organiser ou non un champ potentiel de changement, ce qui permettra de subjectiver l'expérience du toxicomane en lui donnant sens et valeur de vie. Le travail thérapeutique proposé, soucieux de la prévention des rechutes toxicomaniaques et des tentatives de suicide, aborde à la fois les aspects comportementaux et la globalité de la personne toxicomane. Au niveau de la clinique, ces modalités recherchées impliquent des aménagements qui seraient incompréhensibles sans cette approche spécifique aux toxicomanes. -- The thesis presented hereby belongs to the research who aims to the deep compréhension of the origins, of the development and the dynamics of the psychopathology of drug addiction. The research hypothesis is that the choice of using drugs, in order to obtain an immediate pleasure, is the main factor of the psychic dynamics of drug addicts, regardless the différence in regard to the organization of their personality. This choice is supposed to be at the origin of their toxic strategy, which allows them to handle with the psychic tensions as a self-heallng method. We have called toxic stratégies the signs that an unconscious dynamic is in plaœ and can be modified. The contents, which refer explicitiy or at a latent level to the toxic element, are the signs which the therapist is meant to "hear" and elaborate thoroughly. The aim is thereby to draw out the toxic strategy in use inside the treatment of drug users, to detect their various modes of expression. In order to achieve a better understanding of the way the recourse to a real, omnipotent, inanimate mean, placed on the outside of the mental function, such as drugs, we examine how those toxic stratégies tends to obscure the trail of the mental function and to maintain the defense system, which abolishes, among others, every therapeutic alliance, whenever it is possible to obtain one. The specificity of this dinical domain wouldn't be the object-drug (the toxic), its effects or its properties, but the modalities of choosing it and those of its function. The relapse or the interruption of treatment are considered as extemal operational criteria, which are meant to reveal the failure of the therapeutic process, which for the therapist is not sufficiently familiar to deal with the toxic stratégies of the patients. To a better understanding of the function of toxic stratégies in the therapeutic process, we are following three axes of research: 1. The drawing out and the classification of the toxic stratégies. 2. "The cases analysis of theraples with relapse, regarding the presence and évolution of toxic stratégies or not. 3. The cases analysis of advanced therapies without relapse, regarding the awaneness and consciousness of the toxic function, leading to the diminution or abandon of the use of these stratégies. The adopted method consists of the content analysis of the patients' sayings, taken out of the therapeutic treatment, which is characterized by interactive communication, defined by an institutional third. In the case of therapeutic failures, we need also to look for the causes in the particular feelings of the therapists towards their patients, especially at the moment of the introduction of the toxic stratégies during the therapeutic process. Whether or not these toxic stratégies will be taken in to considération inside the process, will define the possibilités of the therapist to organize, or not, an area of change; in order to facilitate him to subjectivate the experience of the drug addict, by giving sense to it and make it valuable for his life. The therapeutic work proposed, with a view to prevent from relapses of the drug addicts and the attempted suicides, treats both the behavioral aspects, and the addict as a whole person. Regarding the clinical practice, these modalities which need to be found demanding adjustments. Without this specific proposed approach, these forms of therapeutic failures would remain unexplained

NUCLEOLYTIC ACTIVITY OF LENTIL SEEDLINGS PURIFICATION AND PROPERTIES STUDY OF AN ENDONUCLESE

ΜΙΑ ΝΕΑ ΕΝΔΟΝΟΥΚΛΕΑΣΗ ΠΟΥ Η ΔΡΑΣΗ ΤΗΣ ΕΞΑΡΤΑΤΑΙ ΑΠΟ ΤΗΝ ΠΑΡΟΥΣΙΑ ΚΑΤΙΟΝΤΩΝ ΑΣΒΕΣΤΙΟΥ ΑΠΟΜΟΝΩΘΗΚΕ ΑΠΟ ΣΠΕΡΜΑΤΑ ΦΑΚΗΣ ΠΟΥ ΒΛΑΣΤΗΣΑΝ ΕΠΙ 84 ΩΡΕΣ ΣΕ 21,5+ΙC ΑΠΟΥΣΙΑ ΦΩΤΟΣ ΜΕ ΧΡΩΜΑΤΟΓΡΑΦΙΑ ΣΕ ΣΤΗΛΕΣ ΚΑΘΑΡΙΣΘΗΚΕ 2000 ΦΟΡΕΣ. ΤΟ ΕΝΖΥΜΟ ΑΥΤΟ (ΝΟΥΚΛΕΑΣΗ ΤΗΣ ΦΑΚΗΣ) ΕΧΕΙ ΒΕΛΤΙΣΤΟ ΔΡΑΣΤΙΚΟΤΗΤΑΣ ΣΤΟ PH 8 ΚΑΙ ΙΣΟΗΛΕΚΤΡΙΚΟ ΣΗΜΕΙΟ PI 4.6. ΕΙΝΑΙ ΜΟΝΟΜΕΡΕΣ, ΜΟΡΙΑΚΟΥ ΒΑΡΟΥΣ 39 KDA ΚΑΙ ΥΔΡΟΛΥΕΙ DNA, RNA ΚΑΙ ΤΟΝ 3' ΔΕΣΜΟ ΤΟΥ 3' _ΑΜΡ. ΑΠΕΛΕΥΘΕΡΩΝΕΙ ΝΟΥΚΛΕΟΤΙΔΙΑ ΜΕ ΤΗ ΦΩΣΦΟΡΙΚΗ ΟΜΑΔΑ ΣΤΗ 5' ΘΕΣΗ. Η ΠΡΟΤΙΜΗΣΗ ΤΟΥ ΠΡΟΣ ΤΑ ΦΥΣΙΚΑ ΥΠΟΣΤΡΩΜΑΤΑ ΚΑΙ ΣΥΝΘΕΤΙΚΑ ΟΜΟΠΟΛΥΡΙΒΟΝΟΥΚΛΕΟΤΙΔΙΑ ΑΚΟΛΟΥΘΕΙ ΤΗΝ ΕΞΗΣ ΣΕΙΡΑ: POLYU>SSDNA>POLYI>POLYA> DSDNA>SSRNA=DSRNA=POLYC>POLYG=0. ΟΠΩΣ ΠΡΟΚΥΠΤΕΙ ΑΠΟ ΤΗ ΔΡΑΣΗ ΤΟΥ ΑΠΕΝΑΝΤΙ ΣΤΟ ΕΠΙΣΗΜΑΣΜΕΝΟ ΣΤΗ 5' ΘΕΣΗ ΜΕ ^32Ρ ΔΕΟΞΥΔΕΚΑΝΟΥΚΛΕΟΤΙΔΙΟ D- ^32PCPCPTPGPGPCPAPG PTPT Η ΠΡΟΤΙΜΗΣΗ ΤΟΥ ΠΡΟΣ ΤΟΥΣ ΔΕΣΜΟΥΣ ΤΩΝ ΝΟΥΚΛΕΟΤΙΔΙΩΝ ΑΚΟΛΟΥΘΕΙ ΤΗ ΣΕΙΡΑ: T PT>T PG>G PT=G PC>A PG>G PG>G PC= C PT= C PA=0. ΑΠΟ ΕΝΑΝ ΑΡΙΘΜΟ ΑΠΟΦΩΣΦΟΡΥΛΙΩΜΕΝΩΝ ΔΙΝΟΥΚΛΕΟΤΙΔΙΩΝ ΥΔΡΟΛΥΕΙ ΜΟΝΟ ΤΟ GPC ΠΡΟΣ G ΚΑΙ PC. ΤΟ ΕΝΖΥΜΟ ΥΔΡΟΛΥΕΙ ΚΑΤΑ ΠΡΟΤΙΜΗΣΗ ΤΙΣ ΑΛΛΗΛΟΥΧΙΕΣ G PC ΚΑΙ C PG ΚΑΙ ΔΕΥΤΕΡΕΥΟΝΤΩΣ ΤΗΝ U PC, ΟΤΑΝ ΩΣ ΥΠΟΣΤΡΩΜΑ ΧΡΗΣΙΜΟΠΟΙΕΙΤΑΙ 5S RNA ΚΟΥΝΕΛΙΟΥ ΓΝΩΣΤΗΣ ΑΛΛΗΛΟΥΧΙΑΣ ΕΠΙΣΗΜΑΣΜΕΝΟ ΣΤΗ 5' ΘΕΣΗ ΜΕ Χ32Ρ. ΣΥΜΠΕΡΑΣΜΑΤΙΚΑ Η ΝΟΥΚΛΕΑΣΗ ΤΗΣ ΦΑΚΗΣ ΤΑΞΙΝΟΜΕΙΤΑΙ ΩΣ ΦΥΤΙΚΗ ΝΟΥΚΛΕΑΣΗ ΤΥΠΟΥ Ι (EC 3.I.30.2) ΠΟΥ ΥΔΡΟΛΥΕΙ ΚΑΤΑ ΠΡΟΤΙΜΗΣΗ ΔΕΣΜΟΥΣ Τ PN ΚΑΙ G PN (ΟΠΟΥ Ν ΕΙΝΑΙ ΕΝΑΣ ΟΠΟΙΟΣΔΗΠΟΤΕ ΝΟΥΚΛΕΟΖΙΤΗΣ) ΣΤΟ DNA ΚΑΙ G PC ΚΑΙ C PG ΣΤΟ RNA.A NEW CALCIUM DEPENDENT ENDONUCLEASE WAS ISOLATED FROM LENTIL SEEDLINGS GERMINATED FOR 84 H IN THE ABSENCE OF LIGHT (AT 21.5=IC). A 2000-FOLD PURIFICATION WAS ACHIEVED BY EMPLOYING A VARIETY OF CHROMATGRAPHIC PROCEDURES. THE ENZYME(LENTIL NUCLEASE) ACTS OPTIMALLY AT PH 8, AND IT EXHIBITS A PI OF 4.6.; IT IS A 39 KDA MONOMER AND HYDROLYSES DNA, RNA AND THE 3' LINKAGE OF 3' -AMP. THE ENZYME FORMS PRODUCTS WITH THE MONOESTERIFIED PHOSPHATE AT THE 5' POSITION. PREFERENCE TOWARDS NATURAL SUBSTRATES AND SYNTHETIC HOMOPOLYRIBONUCLEOTIDES IS AS FOLLOWS: POLU>SSDNA>POLYI>POLYA>DSDNA>SSRNA=DSRNA=POLYC>POLYG=0.ITS BOND PREFERENCE AS TESTED AGAINST 5' X32P-LABEL-LED DEOXYDECANUCLEOTIDE D- X32 PC PCPTPGPGPCPAPGPTPT IS AS FOLLOWS:T PT>T PG>G PT=G PC>A PG >G PG>C PC=C PT= C PA=O. OUTOF A NUMBER OF DINUCLEOSIDE MONOPHOSPHATES IT HYDROLYZES ONLY THE GPC TO G PLUS PC. THE ENZYME HYDROLYZES PREFERENTIALLY GPC AND CPG SEQUENCES AND SECONDARILY THE U PC SEQUENCE WHEN TESTED AGAINST RABBIT 5S RNA OF KNOWH SEQUENCE. ITIS CONCLUDED THAT LENTIL NUCLEASE IS CLASSIFIED AS A PLANT NUCLEASE I(EC 3.I.30.2) THAT HYDROLYZES PREFERENTIALLY T PN AND G PN (IN WHICH N IS ANY NUCLEOSIDE) BONDS IN DNA AND G PC AND C PG BONDS IN RNA

A Design Language and Tool for X-machines Specification

One of the most essential phases of software development is the system specification. Xmachines is an intuitive formal method which can be easily applied at this phase and also facilitate testing in order to prove the correctness of an implementation with respect to the specification. Although the X-Machine theory is already defined in detail mathematically, there is a lack of automated tools which can facilitate its use. In this paper, a brief introduction to the X-Machine theory is presented and a language for specifying X-Machines is defined, which could act as a communication protocol among various X-Machine tools. In addition, a proof tool is presented which checks special properties of X-Machines that are defined as prerequisites for the X-Machine testing algorithm.

Computational models of collective foraging

In this paper the behaviour of a bee colony is modelled as society of communicating agents acting in parallel and synchronising their behaviour. Two computational approaches for defining the agents behaviour are introduced and compared. Their common features as well as the complementary aspects making them suitable for merging together into a more complex model